I've heard people complain about calluses, and how hard it is to get rid of the stubborn things. But don't be so quick to rub it away! Your body is forming a protective barrier from outside elements, desensitizing it to constant pressure and friction. So maybe you should be grateful those calluses are there, making your feet less sensitive to something that may cause you irritation while you run.
Bottom Line: Thank you callus, for helping me tolerate more pain in order to keep doing what I love to do ;)